The latest ischemic stroke treatment guidelines from the American Heart Association recommend it might be reasonable to consider tenecteplase for ischemic stroke in select patients. Both medications are approved for use in dissolving clots in blocked heart arteries, and tenecteplase is sometimes used off-label to treat ischemic strokes. Tenecteplase is a newer generation medication administered by a single injection into a blocked blood vessel. 8-11, 2022.Īlteplase, the current standard of care for stroke, is administered by injection followed by an hour-long infusion and has been FDA-approved for treating clot-caused strokes since 1996. 3, 2022 - In an international registry, patients with clot-caused strokes (ischemic) treated with the newer generation single injection clot-busting medication tenecteplase had half as many serious complications involving bleeding into the brain compared to people who received the standard medication alteplase, according to preliminary research to be presented at the American Stroke Association’s International Stroke Conference 2022, a world premier meeting for researchers and clinicians dedicated to the science of stroke and brain health to be held in person in New Orleans and virtually, Feb. to investigate its effectiveness in improving stroke outcomes.Įmbargoed until 4 a.m. Large clinical trials are underway across the U.S. Tenecteplase is FDA-approved to treat a heart attack, however, it is not currently approved for stroke treatment.Among patients with clot-caused strokes, those treated with the newer single injection clot-busting medication tenecteplase had half as many serious complications involving bleeding into the brain compared to patients who received alteplase, the current standard medication.
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